Labs: 28-Day Cycle Hormone Test (saliva)

28-day hormone test, which includes:

  • Cortisol
  • DHEA
  • Estradiol
  • Melatonin
  • Progesterone
  • Testosterone

Product Description

The Rhythm Plus™ hormone test is a comprehensive assessment of estradiol, progesterone, and testosterone spanning a full 28 days. Additionally, this hormone testing profile includes the Adrenocortex Stress Profile and the Comprehensive Melatonin Profile to reveal how the sex hormones are influenced by cortisol, DHEA, and melatonin. Hormone imbalances revealed in this hormone test can help illuminate root causes of disorders such as premenstrual syndrome (PMS), infertility, and menstrual irregularities.

Hormonal balance is the key. Research has long shown that fluctuating levels of estradiol, progesterone, and testosterone play a major role in a woman´s overall health.

Hormone imbalances can affect:

Menstrual cycle
Mood swings
Sleep patterns
Appetite level
Sex drive
Chronic hormonal imbalances are implicated in disorders such as:

Breast cancer
Polycystic Ovary Disease
Saliva hormone testing provides a thorough analysis of estradiol and progesterone over a full 28 day cycle. Testosterone is measured once from the 28th day specimen. By utilizing 11 saliva samples for analysis, the relationship and balance of these essential hormones are analyzed more precisely through time. The levels of estradiol and progesterone, as well as the ratio between the two, are clearly graphed for easy reference and patient education.

Unlike serum measurements that typically reflect both bound and unbound fractions of hormones, salivary samples represent only the free (unbound) bioavailable fraction of hormone. Factors that affect binding globulin such as obesity and thyroid function do not influence test results with false high or low test levels.

Rhythm Plus™ is a hormonal test indicated for both premenopausal and perimenopauseal women not currently supplementing with hormones. An analysis of estrogen, progesterone and testosterone can reveal ovulatory function and trends in hormone production. Hormonal imbalances such as unopposed estrogen, high follicular progesterone, anovulation and luteal phase defects are easily identified. This hormone test is especially useful in treatment of patients with chronic gynecologic disorders. Additionally, Rhythm Plus includes a circadian analysis of cortisol, melatonin, and an assay of DHEA.


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The laboratory services are for informational purposes only. It is not the intention of Precision Health Solutions, LLC to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.

Both the physician and the testing laboratory are independent contractors with whom Precision Health Solutions, LLC makes arrangements for your blood tests. Precision Health Solutions, LLC will not be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.